/* ===== Apomorphine ED — design system ===== */
:root{
  --gold:#B8912E;
  --gold-bright:#E6C766;
  --gold-soft:#F3E9CF;
  --crimson:#B31B34;
  --crimson-deep:#8E1B2E;
  --crimson-bright:#E23A4E;
  --ink:#17171B;
  --ink-soft:#4c4c54;
  --muted:#7d7d85;
  --bg:#FAFAF8;
  --bg-panel:#FFFFFF;
  --line:#EAE6DC;
  --ring:0 1px 2px rgba(23,23,27,.04), 0 12px 34px -14px rgba(23,23,27,.14);
  --ring-lift:0 2px 6px rgba(23,23,27,.06), 0 26px 60px -22px rgba(142,27,46,.28);
  --radius:18px;
  --maxw:1120px;
  --font-head:'Space Grotesk','Archivo',system-ui,sans-serif;
  --font-body:'Inter',system-ui,-apple-system,sans-serif;
}

*{box-sizing:border-box}
html{scroll-behavior:smooth}
body{
  margin:0;
  font-family:var(--font-body);
  color:var(--ink);
  background:var(--bg);
  line-height:1.65;
  -webkit-font-smoothing:antialiased;
}
img,svg{max-width:100%;height:auto;display:block}
a{color:var(--crimson);text-decoration:none}
a:hover{text-decoration:underline}

.wrap{max-width:var(--maxw);margin:0 auto;padding:0 24px}

h1,h2,h3,h4{font-family:var(--font-head);font-weight:700;letter-spacing:-.02em;line-height:1.08;color:var(--ink);margin:0}
.eyebrow{
  font-family:var(--font-head);
  text-transform:uppercase;
  letter-spacing:.18em;
  font-size:.72rem;
  font-weight:600;
  color:var(--crimson);
  margin:0 0 14px;
}

/* ===== Header ===== */
.site-header{
  position:sticky;top:0;z-index:50;
  background:rgba(250,250,248,.82);
  backdrop-filter:saturate(160%) blur(12px);
  border-bottom:1px solid var(--line);
}
.nav{display:flex;align-items:center;justify-content:space-between;height:70px}
.brand{display:flex;align-items:center;gap:12px;font-family:var(--font-head);font-weight:700;font-size:1.12rem;letter-spacing:-.02em;color:var(--ink)}
.brand:hover{text-decoration:none}
.brand img{width:38px;height:38px}
.brand span{color:var(--crimson-deep)}
.nav-links{display:flex;gap:30px;align-items:center}
.nav-links a{color:var(--ink-soft);font-weight:500;font-size:.94rem}
.nav-links a:hover{color:var(--crimson);text-decoration:none}
.nav-cta{
  background:var(--crimson-deep);color:#fff !important;
  padding:9px 18px;border-radius:999px;font-family:var(--font-head);font-weight:600;font-size:.9rem;
}
.nav-cta:hover{background:var(--crimson);text-decoration:none}
@media(max-width:820px){.nav-links a:not(.nav-cta){display:none}}
@media(max-width:560px){.nav-links{display:none}}

/* ===== Hero ===== */
.hero{position:relative;overflow:hidden;padding:64px 0 40px}
.hero::before{
  content:"";position:absolute;inset:0;z-index:0;
  background:
    radial-gradient(680px 420px at 78% 30%, rgba(226,58,78,.08), transparent 70%),
    radial-gradient(560px 480px at 12% 8%, rgba(198,162,75,.12), transparent 70%);
}
.hero .wrap{position:relative;z-index:1;display:grid;grid-template-columns:1.05fr .95fr;gap:42px;align-items:center}
.hero h1{font-size:clamp(2.3rem,5vw,3.6rem)}
.hero h1 .grad{
  background:linear-gradient(120deg,var(--crimson) 0%,var(--gold) 100%);
  -webkit-background-clip:text;background-clip:text;color:transparent;
}
.hero p.lede{font-size:1.16rem;color:var(--ink-soft);margin:20px 0 28px;max-width:38ch}
.hero-cta{display:flex;gap:14px;flex-wrap:wrap;align-items:center}
.btn{
  font-family:var(--font-head);font-weight:600;font-size:.98rem;
  padding:13px 26px;border-radius:999px;border:1.5px solid transparent;cursor:pointer;transition:.18s;
  display:inline-flex;align-items:center;gap:8px;
}
.btn-primary{background:var(--crimson-deep);color:#fff}
.btn-primary:hover{background:var(--crimson);text-decoration:none;transform:translateY(-1px)}
.btn-ghost{border-color:var(--line);color:var(--ink);background:#fff}
.btn-ghost:hover{border-color:var(--gold);text-decoration:none}
.hero-art{position:relative}
.hero-badges{display:flex;gap:16px;margin-top:30px;flex-wrap:wrap}
.hero-badges .stat{flex:0 0 auto}
.hero-badges .stat b{font-family:var(--font-head);font-size:1.42rem;color:var(--crimson-deep);display:block;line-height:1.1;white-space:nowrap}
.hero-badges .stat span{font-size:.76rem;color:var(--muted);white-space:nowrap}
@media(max-width:860px){.hero .wrap{grid-template-columns:1fr;gap:8px}.hero-art{order:-1;max-width:360px;margin:0 auto}}

/* ===== Section scaffolding ===== */
section{padding:64px 0}
.section-head{max-width:640px;margin-bottom:40px}
.section-head.center{margin-left:auto;margin-right:auto;text-align:center}
.section-head h2{font-size:clamp(1.8rem,3.6vw,2.5rem)}
.section-head p{color:var(--ink-soft);font-size:1.06rem;margin:14px 0 0}
.alt{background:var(--bg-panel);border-top:1px solid var(--line);border-bottom:1px solid var(--line)}

/* ===== Summary intro ===== */
.summary-grid{display:grid;grid-template-columns:1.1fr .9fr;gap:40px;align-items:center}
.summary-grid ul{list-style:none;padding:0;margin:18px 0 0;display:grid;gap:14px}
.summary-grid li{display:flex;gap:12px;align-items:flex-start;color:var(--ink-soft)}
.summary-grid li svg{flex:0 0 22px;margin-top:3px}
.summary-grid li b{color:var(--ink)}
.pathway-card{background:var(--bg-panel);border:1px solid var(--line);border-radius:var(--radius);padding:26px;box-shadow:var(--ring)}
.pathway-card h3{font-size:1.15rem;margin-bottom:16px}
@media(max-width:820px){.summary-grid{grid-template-columns:1fr;gap:26px}}

/* ===== Cards ===== */
.cards{display:grid;grid-template-columns:repeat(3,1fr);gap:24px}
.card{
  background:var(--bg-panel);border:1px solid var(--line);border-radius:var(--radius);
  padding:30px 28px;box-shadow:var(--ring);position:relative;overflow:hidden;
  transition:.2s;display:flex;flex-direction:column;
}
.card::before{content:"";position:absolute;top:0;left:0;right:0;height:4px;
  background:linear-gradient(90deg,var(--crimson-deep),var(--gold))}
.card:hover{transform:translateY(-4px);box-shadow:var(--ring-lift);border-color:var(--gold-soft)}
.card .icon{width:52px;height:52px;border-radius:14px;display:grid;place-items:center;margin-bottom:18px;
  background:linear-gradient(135deg,var(--gold-soft),#fff);border:1px solid var(--line)}
.card h3{font-size:1.28rem;margin-bottom:10px}
.card p{color:var(--ink-soft);font-size:.98rem;margin:0 0 18px}
.card .card-link{margin-top:auto;font-family:var(--font-head);font-weight:600;font-size:.92rem;color:var(--crimson);display:inline-flex;gap:6px;align-items:center}
.card .card-link:hover{gap:10px;text-decoration:none}
@media(max-width:900px){.cards{grid-template-columns:1fr}}

/* ===== Ranked treatments ===== */
.ranks{display:grid;gap:16px;margin-top:8px}
.rank{
  display:grid;grid-template-columns:56px 1fr auto;gap:20px;align-items:center;
  background:var(--bg-panel);border:1px solid var(--line);border-radius:16px;padding:20px 24px;box-shadow:var(--ring);transition:.18s;
}
.rank:hover{border-color:var(--gold);transform:translateX(3px)}
.rank .num{font-family:var(--font-head);font-weight:700;font-size:1.7rem;
  width:52px;height:52px;border-radius:14px;display:grid;place-items:center;color:#fff;
  background:linear-gradient(135deg,var(--crimson-deep),var(--crimson-bright))}
.rank:nth-child(2) .num{background:linear-gradient(135deg,#9a7a1f,var(--gold-bright))}
.rank:nth-child(3) .num{background:linear-gradient(135deg,#6b6b73,#a9a9b2)}
.rank .r-body h4{font-size:1.15rem;margin-bottom:3px}
.rank .r-body .r-tag{font-size:.82rem;color:var(--crimson);font-weight:600;font-family:var(--font-head);text-transform:uppercase;letter-spacing:.06em}
.rank .r-body p{margin:6px 0 0;color:var(--ink-soft);font-size:.94rem;max-width:56ch}
.rank .r-meta{text-align:right;min-width:96px}
.rank .r-meta .form{font-family:var(--font-head);font-weight:600;color:var(--ink);font-size:.92rem}
.rank .r-meta .note{font-size:.78rem;color:var(--muted)}
@media(max-width:720px){.rank{grid-template-columns:48px 1fr}.rank .r-meta{grid-column:2;text-align:left;margin-top:6px}}

/* ===== Stats band ===== */
.stats-band{display:grid;grid-template-columns:repeat(4,1fr);gap:24px;text-align:center}
.stats-band .s b{font-family:var(--font-head);font-weight:700;font-size:2.3rem;
  background:linear-gradient(120deg,var(--crimson) 0%,var(--gold) 100%);-webkit-background-clip:text;background-clip:text;color:transparent;display:block}
.stats-band .s span{color:var(--ink-soft);font-size:.92rem;display:block;margin-top:4px}
.stats-band .s sup{font-size:.6em;color:var(--crimson);font-weight:700}
@media(max-width:760px){.stats-band{grid-template-columns:repeat(2,1fr);gap:32px 16px}}

/* ===== FAQ ===== */
.faq{max-width:820px;margin:0 auto;display:grid;gap:12px}
.faq-item{background:var(--bg-panel);border:1px solid var(--line);border-radius:14px;overflow:hidden;box-shadow:var(--ring)}
.faq-q{width:100%;text-align:left;background:none;border:0;cursor:pointer;
  padding:20px 24px;font-family:var(--font-head);font-weight:600;font-size:1.05rem;color:var(--ink);
  display:flex;justify-content:space-between;align-items:center;gap:16px}
.faq-q:hover{color:var(--crimson)}
.faq-q .chev{flex:0 0 auto;transition:transform .22s;color:var(--crimson)}
.faq-item.open .faq-q .chev{transform:rotate(180deg)}
.faq-a{max-height:0;overflow:hidden;transition:max-height .28s ease}
.faq-a p{margin:0;padding:0 24px 20px;color:var(--ink-soft);font-size:.98rem}

/* ===== Sources / citations ===== */
.sources ol{margin:0;padding-left:22px;display:grid;gap:12px;color:var(--ink-soft);font-size:.92rem}
.sources li{padding-left:6px}
.sources a{word-break:break-word}
.cite{font-size:.72em;vertical-align:super;color:var(--crimson);font-weight:700;text-decoration:none}
.cite:hover{text-decoration:underline}

/* ===== Disclaimer / footer ===== */
.disclaimer{background:#FBF4EE;border:1px solid var(--gold-soft);border-left:4px solid var(--gold);border-radius:12px;padding:20px 24px;color:var(--ink-soft);font-size:.9rem}
.disclaimer b{color:var(--ink)}
.site-footer{background:#1A1A1E;color:#c7c7cf;padding:48px 0 34px;margin-top:8px}
.site-footer .wrap{display:grid;grid-template-columns:1.4fr 1fr;gap:32px;align-items:start}
.site-footer .brand{color:#fff}
.site-footer .brand span{color:#fff}
.site-footer p{font-size:.9rem;color:#9a9aa4;max-width:46ch;margin:14px 0 0}
.site-footer .f-links{display:flex;gap:26px;flex-wrap:wrap;justify-content:flex-end}
.site-footer .f-links a{color:#c7c7cf;font-size:.9rem}
.site-footer .f-links a:hover{color:var(--gold-bright)}
.site-footer .copy{grid-column:1/-1;border-top:1px solid #2c2c32;margin-top:14px;padding-top:20px;font-size:.82rem;color:#7c7c86}
@media(max-width:760px){.site-footer .wrap{grid-template-columns:1fr}.site-footer .f-links{justify-content:flex-start}}

/* ===== Article / subpage layouts ===== */
.page-hero{position:relative;overflow:hidden;padding:56px 0 40px;border-bottom:1px solid var(--line)}
.page-hero::before{content:"";position:absolute;inset:0;z-index:0;
  background:radial-gradient(620px 380px at 82% 20%, rgba(226,58,78,.07), transparent 70%),
             radial-gradient(520px 420px at 6% 10%, rgba(198,162,75,.12), transparent 70%)}
.page-hero .wrap{position:relative;z-index:1}
.crumbs{font-family:var(--font-head);font-size:.82rem;color:var(--muted);margin-bottom:18px}
.crumbs a{color:var(--muted)}
.crumbs a:hover{color:var(--crimson)}
.crumbs span{color:var(--crimson);font-weight:600}
.page-hero h1{font-size:clamp(2rem,4.4vw,3.1rem);max-width:20ch}
.page-hero .sub{font-size:1.14rem;color:var(--ink-soft);margin:18px 0 0;max-width:60ch}

.article{padding:56px 0}
.article .wrap{max-width:820px}
.prose > *{margin:0 0 20px}
.prose h2{font-size:1.7rem;margin:44px 0 14px;padding-top:6px}
.prose h3{font-size:1.22rem;margin:30px 0 10px}
.prose p,.prose li{color:var(--ink-soft);font-size:1.04rem}
.prose strong,.prose b{color:var(--ink)}
.prose ul{padding-left:0;list-style:none;display:grid;gap:12px}
.prose ul li{position:relative;padding-left:24px}
.prose ul li::before{content:"";position:absolute;left:0;top:10px;width:9px;height:9px;border-radius:3px;
  background:linear-gradient(135deg,var(--crimson-deep),var(--gold))}
.prose figure{margin:30px 0}
.prose figure img{margin:0 auto}
.prose figure figcaption{text-align:center;font-size:.86rem;color:var(--muted);margin-top:10px}
.callout{background:#FBF4EE;border:1px solid var(--gold-soft);border-left:4px solid var(--gold);
  border-radius:12px;padding:20px 24px;color:var(--ink-soft);font-size:.98rem}
.callout b{color:var(--ink)}
.pull{background:var(--bg-panel);border:1px solid var(--line);border-radius:var(--radius);
  padding:26px 28px;box-shadow:var(--ring);font-family:var(--font-head);font-weight:500;
  font-size:1.24rem;line-height:1.4;color:var(--ink)}
.pull span{background:linear-gradient(120deg,var(--crimson) 0%,var(--gold) 100%);
  -webkit-background-clip:text;background-clip:text;color:transparent}

/* comparison table */
.ctable{width:100%;border-collapse:collapse;font-size:.95rem;overflow:hidden;
  border:1px solid var(--line);border-radius:14px}
.ctable th,.ctable td{padding:14px 16px;text-align:left;border-bottom:1px solid var(--line)}
.ctable thead th{font-family:var(--font-head);font-size:.82rem;text-transform:uppercase;
  letter-spacing:.06em;color:#fff;background:linear-gradient(120deg,var(--crimson-deep),var(--crimson))}
.ctable tbody tr:last-child td{border-bottom:0}
.ctable tbody tr:nth-child(even){background:#FBFAF6}
.ctable td:first-child{font-weight:600;color:var(--ink);font-family:var(--font-head)}
.table-scroll{overflow-x:auto;border-radius:14px}

.next-cards{display:grid;grid-template-columns:1fr 1fr;gap:18px;margin-top:14px}
.next-card{background:var(--bg-panel);border:1px solid var(--line);border-radius:16px;padding:22px 24px;
  box-shadow:var(--ring);transition:.18s;display:block}
.next-card:hover{transform:translateY(-3px);box-shadow:var(--ring-lift);border-color:var(--gold-soft);text-decoration:none}
.next-card .k{font-family:var(--font-head);font-size:.76rem;text-transform:uppercase;letter-spacing:.12em;color:var(--crimson)}
.next-card h4{font-size:1.12rem;margin:8px 0 4px}
.next-card p{color:var(--ink-soft);font-size:.92rem;margin:0}
@media(max-width:680px){.next-cards{grid-template-columns:1fr}}

/* reveal on scroll */
.reveal{opacity:0;transform:translateY(16px);transition:opacity .6s ease,transform .6s ease}
.reveal.in{opacity:1;transform:none}
@media(prefers-reduced-motion:reduce){.reveal{opacity:1;transform:none;transition:none}html{scroll-behavior:auto}}